Custom In Vitro Diagnostic Surfaces

The Success of Your Application Lies in its Surface

Blood and serum samples contain biological materials that can cause significant background noise and interfere with the detection of trace biomarkers in different diagnostic applications.

SurModics’ specialized polymer coatings have intrinsic non-fouling properties that prevent the adsorption of these unwanted proteins to plastics, metals, glass, and other substrates, thus decreasing background while increasing the signal, and eliminating time-comsuming blocking steps for increased processing speed. A SurModics In Vitro Diagnostic Surface is composed of three distinct parts: 

  • A photo-reactive group to covalently couple the polymer backbone to the surface, including plastics, metals, glass, and latex

  • A passivating polymer to prevent nonspecific binding of unwanted biomaterial in samples while providing a three-dimensional environment to aid in hybridizations or other associations between related biomolecules

  • A reactive group, or biocapture chemistry, to bind the antibody, ligand, antigen, DNA, microRNA, or other biomolecule

SurModics’ surfaces include: 

We also offer surfaces not intended to capture analytes, but rather to increase the wettability, hemocompatibility, or lubricity of surfaces in diagnostics instruments and other test components.

Learn more about SurModics In Vitro Diagnostic Surfaces