DIARECT Autoimmune Antigens

Human recombinant autoimmune antigens are used for the development and production of autoimmunity diagnostic kits. DIARECT autoimmune antigens offer outstanding assay performance with the most complete panel of recombinant and native autoimmune antigens in all diagnostic applications. Whether in ELISAs, dot or blot methods, DIARECT antigens have a proven track record for quality and sensitivity.

SurModics is the exclusive distributor of DIARECT AG's human recombinant autoimmune antigens in North America.

Poster Presentations:
Use of recombinant autoantigens in profiling of PBC-associated antobidies

Detection of autoantibodies to GP2, the major zymogen granule membrane glycoprotein, by novel test systems

Note: Antigens are available in 50 µg and 1.0 mg sizes unless otherwise noted

Product Code Expression System Antigen Description Clinical Association
A12100 A12101 Baculovirus/Insect Cell Thyroid Peroxidase (TPO) Graves' Disease
A12200 A12201 Native Thyroglobulin (non recomb.) Hashimoto Thyroiditis
A12300 A12301 E. coli dsDNA (plasmid) Systemic Lupus Erythematosus (SLE)
A15400 A15401 Baculovirus/Insect Cell Proliferating Cell Nuclear Antigen (PCNA)
A17400 A17401 E. coli Ro/SS-A (60 kDa; recomb.)

SCLE/Neonatal LE/Sjøgren's Syndrome
A15500 A15501 Baculovirus/Insect Cell Ro/SS-A (60 kDa; non recomb.; bovine)
A12700 A12701 Baculovirus/Insect Cell Ro/SS-A (52 kDa)
A12800 A12801 Baculovirus/Insect Cell La/SS-B
A14100 A14101 Baculovirus/Insect Cell Ribosomal Phosphoprotein P0 SLE (CNS involvement)
A13000 A13001 E. coli U1-snRNP 68/70 kDa

Mixed Connective Tissue Disease/SLE
A13100 A13101 Baculovirus/Insect Cell U1-snRNP A
A13200 A13201 Baculovirus/Insect Cell U1-snRNP C
A13300 A13301 Baculovirus/Insect Cell U-snRNP B/B'
A12900 A12901 Baculovirus/Insect Cell Histidyl-tRNA Synthetase (Jo-1) Polymyositis / Dermatomyositis
A15600 A15601 Baculovirus/Insect Cell Threonyl-tRNA Synthetase (PL-7)
A15700 A15701 Baculovirus/Insect Cell Alanyl-tRNA Synthetase (PL-12)
A18400 A18401 Baculovirus/Insect Cell SRP54
A18100 A18101 Baculovirus/Insect Cell Mi-2 Dermatomyositis
A16000 A16001 Baculovirus/Insect Cell PM/Scl 100 Polymyositis / Scleroderma
A12400 A12401 Baculovirus/Insect Cell DNA Topoisomerase I (Scl-70; full length) Scleroderma (diffuse)
A14500 A14501 Baculovirus/Insect Cell DNA Topoisomerase I (Scl-70; truncated)
A12500 A12501 Baculovirus/Insect Cell Centromere Protein B (CENP-B) Scleroderma (CREST)
A16900 A16901 Baculovirus/Insect Cell Centromere Protein A (CENP-A)
A17300 A17301 Baculovirus/Insect Cell Ku (p70/p80) Overlap Syndrome
A13500 A13501 Baculovirus/Insect Cell Cytochrome P450 2D6 (LKM 1) Autoimmune Hepatitis II
A13700 A13701 Baculovirus/Insect Cell Formiminotransferase Cyclodeaminase (LC1)
A18000 A18001 Baculovirus/Insect Cell M2 Primary Biliary Cirrhosis
A18900 A18901 Baculovirus/Insect Cell SP100
A19000 A19001 Baculovirus/Insect Cell gp210
A19400 A19401 Baculovirus/Insect Cell Nup62
A14900 A14901 Baculovirus/Insect Cell β2 Glycoprotein I (Apolipoprotein H) Thromboembolic Syndrome

A19100  A19101

 Baculovirus/Insect Cell Annexin V
A15900 A15901 Baculovirus/Insect Cell Glomerular Basement Membrane (undissociated) Goodpasture's Syndrome
A16800 A16801 Baculovirus/Insect Cell Glomerular Basement Membrane (dissociated)
A14400 A14401 E. coli Tissue Transglutaminase (tTG) Celiac Disease
A15200 A15201 Baculovirus/Insect Cell Tissue Transglutaminase (tTG)
A19500 A19501 E. coli Gliadin (recombinant; deamidated)
A17100 A17101 Non-Recombinant Gliadin (IgA) (non recomb.; 0.6 mL; 6.0 mL) Gastrointestinal/Celiac Disease
A17200 A17201 Non-Recombinant Gliadin (IgG) (non recomb.; 0.3 mL; 3.0 mL)
A19600 A19601 Baculovirus/Insect Cell GP2 Crohn's Disease
A16700 A16701 Baculovirus/Insect Cell Intrinsic Factor Pernicious Anemia
A18500 A18501 Native Myeloperoxidase (MPO) (non-recombinant) Systemic Vasculitides
A18600 A18601 Human peripheral blood leucocytes Proteinase 3 (PR3; non-recombinant) Systemic Vasculitides/ Wegener's Granulomatosis
A33200 A33201 Produced by human heterohybridoma cell line dsDNA-mAb32 Suitable for FARR and Crithidia IIFT
A33300 A33301 Produced by human heterohybridoma cell line dsDNA-mAb33 Suitable for ELISA

Learn more about DIARECT autoimmune antigens

Products on this Page: 
Thyroid Peroxidase (TPO) - 50 µg
Thyroid Peroxidase (TPO) - 1.0 mg
Thyroglobulin (non-recombinant) - 50 µg
Thyroglobulin (non-recombinant) - 1.0 mg
dsDNA (plasmid) - 50 µg
dsDNA (plasmid) - 1.0 mg
DNA Topoisomerase (Scl-70, full length) - 50 µg
DNA Topoisomerase (Scl-70, full length) - 1.0 mg
Centromere Protein B (CENP-B) - 50 µg
Centromere Protein B (CENP-B) - 1.0 mg
Ro/SS-A (52 kDa) - 50 µg
Ro/SS-A (52 kDa) - 1.0 mg
La/SS-B - 50 µg
La/SS-B - 1.0 mg
Histidyl-tRNA Synthetase (Jo-1) - 50 µg
Histidyl-tRNA Synthetase (Jo-1) - 1.0 mg
U1-snRNP 68/70 kDa - 50 µg
U1-snRNP 68/70 kDa - 1.0 mg
U1-snRNP A - 50 µg
U1-snRNP A - 1.0 mg
U1-snRNP C - 50 µg
U1-snRNP C - 1.0 mg
U-snRNP B/B' - 50 µg
U-snRNP B/B' - 1.0 mg
Cytochrome P450 2D6 (LKM 1) - 50 µg
Cytochrome P450 2D6 (LKM 1) - 1.0 mg
Formiminotransferase Cyclodeaminase (LC1) - 50 µg
Formiminotransferase Cyclodeaminase (LC1) - 1.0 mg
Ribosomal Phosphoprotein PO - 50 µg
Ribosomal Phosphoprotein PO - 1.0 mg
Tissue Transglutaminase (tTG; expressed in E. coli) - 50 µg
Tissue Transglutaminase (tTG; expressed in E. coli) - 1.0 mg
DNA Topoisomerase (Scl-70, truncated) - 50 µg
DNA Topoisomerase (Scl-70; truncated) - 1.0 mg
β2 Glycoprotein I (Apolipoprotein H) - 50 µg
β2 Glycoprotein I (Apolipoprotein H) - 1.0 mg
Tissue Transglutaminase (tTG; expressed in Baculovirus/Sf9) - 50 µg
Tissue Transglutaminase (tTG; expressed in Baculovirus/Sf9) - 1.0 mg
Proliferating Cell Nuclear Antigen (PCNA) - 50 µg
Proliferating Cell Nuclear Antigen (PCNA) - 1.0 mg
Ro/SS-A(60 kDa, non-recombinant, bovine) - 50 µg
Ro/SS-A(60 kDa, non-recombinant, bovine) - 1.0 mg
Threonyl-tRNA Synthetase (PL-7) - 50 µg
Threonyl-tRNA Synthetase (PL-7) - 1.0 mg
Alanyl-tRNA Synthetase (PL-12) - 50 µg
Alanyl-tRNA Synthetase (PL-12) - 1.0 mg
Glomerular Basement Membrane (undissociated) - 50 µg
Glomerular Basement Membrane (undissociated) - 1.0 mg
PM/Scl 100 (BV) - 50 µg
PM/Scl 100 (BV) - 1.0 mg
Intrinsic Factor (IF) - 50 µg
Intrinsic Factor (IF) - 1.0 mg
Glomerular Basement Membrane (GBM; dissociated) - 50 µg
Glomerular Basement Membrane (GBM; dissociated) - 1.0 mg
Centromere Protein A (CENP-A) - 50 µg
Centromere Protein A (CENP-A) - 1.0 mg
Gliadin (IgA) (non-recombinant - 0.6 mL)
Gliadin (IgA) (non-recombinant - 6.0 mL)
Gliadin (IgG) (non-recombinant - 0.3 mL)
Gliadin (IgG) (non-recombinant - 3.0 mL)
Ku (p70/p80) - 50 µg
Ku (p70/p80) - 1.0 mg
Ro/SS-A(60 kDa, recombinant) - 50 µg
Ro/SS-A(60 kDa, recombinant) - 1.0 mg
M2 - 50 µg
M2 - 1.0 mg
Mi-2 - 50 µg
Mi-2 - 1.0 mg
Signal Recognition Particle (SRP54) - 50 µg
Signal Recognition Particle (SRP54) - 1.0 mg
Myeloperoxidase (MPO); non-recombinant) - 50 µg
Myeloperoxidase (MPO); non-recombinant) - 1.0 mg
Proteinase 3 (PR3; non-recombinant) - 50 µg
Proteinase 3 (PR3; non-recombinant) - 1.0 mg
SP100 - 50 µg
SP100 - 1.0 mg
gp210 - 50 ug
gp210 - 1.0 mg
Nup62 - 50 ug
Nup62 - 1.0 mg
Gliadin (recombinant; deamidated) - 50 ug
Gliadin (recombinant; deamidated) - 1.0 mg
GP2 - 50 ug
GP2 - 1.0 mg
Annexin V - 50 ug
Annexin V - 1.0 mg
dsDNA-mAb32 - 50 µg
dsDNA-mAb32 - 1.0 mg
dsDNA-mAb33) - 50 µg
dsDNA-mAb33) - 1.0 mg