DIARECT Autoimmune Antigens

Human recombinant autoimmune antigens are used for the development and production of autoimmunity diagnostic kits. DIARECT autoimmune antigens offer outstanding assay performance with the most complete panel of recombinant and native autoimmune antigens in all diagnostic applications. Whether in ELISAs, dot or blot methods, DIARECT antigens have a proven track record for quality and sensitivity.

SurModics is the exclusive distributor of DIARECT AG's human recombinant autoimmune antigens in North America.

Click here to view product sheets on several of the available antigens

Poster Presentations:
Use of recombinant autoantigens in profiling of PBC-associated antibodies

Detection of autoantibodies to GP2, the major zymogen granule membrane glycoprotein, by novel test systems

Note: Antigens are available in 50 µg and 1.0 mg sizes unless otherwise noted

Antigen

Origin

Clinical Association

Product Code

Thyroid Peroxidase (TPO)

Insect cell expression

Graves‘ Disease

A12100

A12101

Thyroglobulin

Native, human

Hashimoto Thyroiditis

A12200

A12201

DNA Topoisomerase I

(Scl-70; full length)

Insect cell expression

Scleroderma (diffuse)

A12400

A12401

DNA Topoisomerase I

(Scl-70; truncated)

Insect cell expression

A14500

A14501

Centromere Protein B

(CENP-B)

Insect cell expression

Scleroderma (CREST)

A12500

A12501

Centromere Protein A

(CENP-A)

Insect cell expression

A16900

A16901

PM/Scl 100

Insect cell expression

Myositis / Scleroderma / Overlap

A16000

A16001

PM/Scl 75

Insect cell expression

A17000

A17001

Ro/SS-A (60 kDa)

Bacterial expression

SCLE / Neonatal LE / Sjøgren’s Syndrome

A17400

A17401

Ro/SS-A (60 kDa)

Native, bovine

A15500

A15501

Ro/SS-A (52 kDa)

Insect cell expression

A12700

A12701

La/SS-B

Insect cell expression

A12800

A12801

Histidyl-tRNA Synthetase

(Jo-1)

Insect cell expression

Poly/Dermatomyositis

A12900

A12901

Threonyl-tRNA Synthetase

(PL-7)

Insect cell expression

A15600

A15601

Alanyl-tRNA Synthetase

(PL-12)

Insect cell expression

A15700

A15701

Mi-2

Insect cell expression

Dermatomyositis

A18100

A18101

SRP54

Insect cell expression

Poly/Dermatomyositis

A18400

A18401

U1-snRNP 68/70 kDa

Bacterial expression

MCTD/SLE

A13000

A13001

U1-snRNP A

Insect cell expression

A13100

A13101

U1-snRNP C

Insect cell expression

A13200

A13201

U-snRNP B/B´

Insect cell expression

A13300

A13301

Ku (p70/p80)

Insect cell expression

Overlap Syndrome / Myositis / SLE

A17300

A17301

Ribosomal

Phosphoprotein P0

Insect cell expression

SLE (CNS involvement)

A14100

A14101

Ribosomal Phosphoprotein

P1

Insect cell expression

SLE

A14200

A14201

Ribosomal Phosphoprotein

P2

Insect cell expression

A14300

A14301

dsDNA (plasmid)

Bacterial expression

A12300

A12301

Proliferating Cell Nuclear

Antigen (PCNA)

Insect cell expression

A15400

A15401

Cytochrome P450 2D6

(LKM 1)

Insect cell expression

Autoimmune Hepatitis II

A13500

A13501

Formiminotransferase Cyclodeaminase (LC1)

Insect cell expression

A13700

A13701

M2

Insect cell expression

Primary Biliary Cirrhosis

A18000

A18001

BCOADC-E2

Insect cell expression

A17700

A17701

OGDC-E2

Insect cell expression

A17800

A17801

PDC-E2

Insect cell expression

A17900

A17901

Sp100

Insect cell expression

A18900

A18901

gp210

Insect cell expression

A19000

A19001

Nup62

Insect cell expression

A19400

A19401

b2-Glycoprotein 1

(Apolipoprotein H)

Insect cell expression

Thromboembolic Syndrome

A14900

A14901

Annexin V

Insect cell expression

A19100

A19101

Tissue Transglutaminase

(tTG)

Bacterial expression

Celiac Disease

A14400

A14401

Tissue Transglutaminase

(tTG)

Insect cell expression

A15200

A15201

Gliadin (deamidated)

Bacterial expression

A19500

A19501

Glomerular Basement

Membrane (GBM; dissociated)

Insect cell expression

Goodpasture Syndrome

A16800

A16801

Intrinsic Factor

Insect cell expression

Pernicious Anemia

A16700

A16701

Myeloperoxidase (MPO)

Native, human

Systemic Vasculitides

A18500

A18501

Proteinase 3 (PR3)

Native, human

Systemic Vasculitides / Wegener's Granulomatosis

A18600

A18601

BPI

Native, human

ANCA target in diverse diseases

A19200

A19201

LAMP-2

Insect cell expression

Focal Necrotizing Glomerulonephritis

A19300

A19301

GP2

Insect cell expression

Crohn's Disease

A19600

A19601

 

Learn more about DIARECT autoimmune antigens

Products on this Page: 
Thyroid Peroxidase (TPO) - 50 µg
Thyroid Peroxidase (TPO) - 1.0 mg
Thyroglobulin (non-recombinant) - 50 µg
Thyroglobulin (non-recombinant) - 1.0 mg
dsDNA (plasmid) - 50 µg
dsDNA (plasmid) - 1.0 mg
DNA Topoisomerase (Scl-70, full length) - 50 µg
DNA Topoisomerase (Scl-70, full length) - 1.0 mg
Centromere Protein B (CENP-B) - 50 µg
Centromere Protein B (CENP-B) - 1.0 mg
Ro/SS-A (52 kDa) - 50 µg
Ro/SS-A (52 kDa) - 1.0 mg
La/SS-B - 50 µg
La/SS-B - 1.0 mg
Histidyl-tRNA Synthetase (Jo-1) - 50 µg
Histidyl-tRNA Synthetase (Jo-1) - 1.0 mg
U1-snRNP 68/70 kDa - 50 µg
U1-snRNP 68/70 kDa - 1.0 mg
U1-snRNP A - 50 µg
U1-snRNP A - 1.0 mg
U1-snRNP C - 50 µg
U1-snRNP C - 1.0 mg
U-snRNP B/B' - 50 µg
U-snRNP B/B' - 1.0 mg
Cytochrome P450 2D6 (LKM 1) - 50 µg
Cytochrome P450 2D6 (LKM 1) - 1.0 mg
Formiminotransferase Cyclodeaminase (LC1) - 50 µg
Formiminotransferase Cyclodeaminase (LC1) - 1.0 mg
Ribosomal Phosphoprotein PO - 50 µg
Ribosomal Phosphoprotein PO - 1.0 mg
Tissue Transglutaminase (tTG; expressed in E. coli) - 50 µg
Tissue Transglutaminase (tTG; expressed in E. coli) - 1.0 mg
DNA Topoisomerase (Scl-70, truncated) - 50 µg
DNA Topoisomerase (Scl-70; truncated) - 1.0 mg
β2 Glycoprotein I (Apolipoprotein H) - 50 µg
β2 Glycoprotein I (Apolipoprotein H) - 1.0 mg
Tissue Transglutaminase (tTG; expressed in Baculovirus/Sf9) - 50 µg
Tissue Transglutaminase (tTG; expressed in Baculovirus/Sf9) - 1.0 mg
Proliferating Cell Nuclear Antigen (PCNA) - 50 µg
Proliferating Cell Nuclear Antigen (PCNA) - 1.0 mg
Ro/SS-A(60 kDa, non-recombinant, bovine) - 50 µg
Ro/SS-A(60 kDa, non-recombinant, bovine) - 1.0 mg
Threonyl-tRNA Synthetase (PL-7) - 50 µg
Threonyl-tRNA Synthetase (PL-7) - 1.0 mg
Alanyl-tRNA Synthetase (PL-12) - 50 µg
Alanyl-tRNA Synthetase (PL-12) - 1.0 mg
Glomerular Basement Membrane (undissociated) - 50 µg
Glomerular Basement Membrane (undissociated) - 1.0 mg
PM/Scl 100 (BV) - 50 µg
PM/Scl 100 (BV) - 1.0 mg
Intrinsic Factor (IF) - 50 µg
Intrinsic Factor (IF) - 1.0 mg
Glomerular Basement Membrane (GBM; dissociated) - 50 µg
Glomerular Basement Membrane (GBM; dissociated) - 1.0 mg
Centromere Protein A (CENP-A) - 50 µg
Centromere Protein A (CENP-A) - 1.0 mg
Gliadin (IgA) (non-recombinant - 0.6 mL)
Gliadin (IgA) (non-recombinant - 6.0 mL)
Gliadin (IgG) (non-recombinant - 0.3 mL)
Gliadin (IgG) (non-recombinant - 3.0 mL)
Ku (p70/p80) - 50 µg
Ku (p70/p80) - 1.0 mg
Ro/SS-A(60 kDa, recombinant) - 50 µg
Ro/SS-A(60 kDa, recombinant) - 1.0 mg
M2 - 50 µg
M2 - 1.0 mg
Mi-2 - 50 µg
Mi-2 - 1.0 mg
Signal Recognition Particle (SRP54) - 50 µg
Signal Recognition Particle (SRP54) - 1.0 mg
Myeloperoxidase (MPO); non-recombinant) - 50 µg
Myeloperoxidase (MPO); non-recombinant) - 1.0 mg
Proteinase 3 (PR3; non-recombinant) - 50 µg
Proteinase 3 (PR3; non-recombinant) - 1.0 mg
SP100 - 50 µg
SP100 - 1.0 mg
gp210 - 50 ug
gp210 - 1.0 mg
Nup62 - 50 ug
Nup62 - 1.0 mg
Gliadin (recombinant; deamidated) - 50 ug
Gliadin (recombinant; deamidated) - 1.0 mg
GP2 - 50 ug
GP2 - 1.0 mg
Annexin V - 50 ug
Annexin V - 1.0 mg