StabilCoat® and 5X StabilCoat® Immunoassay Stabilizers

SurModics StabilCoat® Immunoassay Stabilizer (also available in a 5X concentrated solution) has the exceptional and rare ability to not only preserve the conformation and activity of dried proteins in immunoassays, but to also function as an excellent blocking buffer.

  • StabilCoat Immunoassay Stabilizer is considered the gold standard for stabilizing proteins in the dried state.
  • StabilCoat solution is an excellent blocking agent that can be dried down or used as a blocker for same-day assays.
  • Simply substitute StabilCoat Stabilizer for your usual blocking solution for easy incorporation into most assay protocols.
  • Use it to stabilize antibodies, antigens, or enzymes on an assortment of immunoassay components, such as polystyrene plates, tubes, glass, membranes, and filter paper. 
Product Codes

SC01 - StabilCoat® Immunoassay Stabilizer; SC05 - 5X StabilCoat® Immunoassay Stabilizer

Available Sizes

50 mL sample (SC01 only), 100 mL (SC05 only), 1000 mL, 2000 mL

Storage

Product should be refrigerated or stored at room temperature.

Bovine Protein

Yes

Dry Weight (g/mL)

0.098 - 0.113 (same for 5X StabilCoat stabilizer when diluted 1:5)

Product Buffer

PBS

pH

7.0 - 7.4

Preservative

None. StabilCoat protein stabilizer is filtered through a 0.1-micron filter. Customers may add preservative to this product, if needed. SurModics recommends the use of ProClin™ at the concentration recommended by the manufacturer of the ProClin.

Shelf Life

3 years (SC01); 2 years (SC05)

Stability Data

Stability tests were performed with StabilCoat stabilizer using either rabbit monoclonal or polyclonal IgG antibodies (see graph below). Coated microtiter plates were stabilized with either StabilCoat stabilizer or 1% BSA. The antibody-coated plates were dried and placed at room temperature. Percent retained activity was determined by comparing the activity of the aged antibody-coated microtiter plates to that of freshly coated plates. After 30 months in StabilCoat stabilizer at room temperature, the monoclonal antibody retained 70% activity and the polyclonal antibody retained 95% activity.

Product Brochure:  "SurModics Immunoassay Stabilizers"

StabilCoat Immunoassay Stabilizer/Blocker "Recommendations for Use"